COMPOSITION FOR TREATING OR PRVENTING OSTEOARTHRITIS

The present invention may provide a pharmaceutical composition for preventing or treating osteoarthritis, including a carrier carrying a type II collagen peptide and rapamycin. The present invention preferably can reduce an inflammatory response caused by inflammatory immune cells occurring in the j...

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Bibliographic Details
Main Authors CHOI JEONG WON, NA HYUN SIK, KIM BYUNG SOO, CHO MI LA, JHUN JOO YEON, SOHN HEE SU
Format Patent
LanguageEnglish
Korean
Published 25.01.2023
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Summary:The present invention may provide a pharmaceutical composition for preventing or treating osteoarthritis, including a carrier carrying a type II collagen peptide and rapamycin. The present invention preferably can reduce an inflammatory response caused by inflammatory immune cells occurring in the joint, alleviate cartilage destruction and pain accompanied by the inflammatory response, and further regenerate cartilage. Further, the composition of the present invention can be used as medicine for osteoarthritis, and also inflammatory diseases such as myocardial infarction, cerebral infarction, and spinal cord injury or autoimmune diseases such as atopic dermatitis, rheumatoid arthritis, type 1 diabetes, Crohn's disease, lupus, etc. by carrying other disease-related antigens. 본 발명은 제 2형 콜라겐 펩타이드 및 라파마이신을 담지하는 전달체를 포함하는 골관절염의 예방 또는 치료용 약학 조성물을 제공할 수 있다. 이는 바람직하게는 관절에서 발생하는 염증성 면역세포에 의한 염증반응을 감소시키면서, 염증반응으로 수반되는 연골 파괴 및 통증을 완화시키고, 더 나아가서는 연골을 재생시킬 수 있다. 본 발명의 조성물은 더 나아가 골관절염뿐 아니라, 다른 질병 관련 항원을 담지하여 심근경색, 뇌경색, 척추손상 등의 염증성 질환 또는 아토피, 류마티스관절염, 1형 당뇨병, 크론병, 루푸스 등 자가면역질환의 치료제로서 활용할 수 있다.
Bibliography:Application Number: KR20220092632