NANOPARTICLE CONJUGATE AND METHOD FOR DETECTING TARGET METERIAL USING THE SAME

The present invention relates to a nanoparticle conjugate and a method for detecting a target substance using the same. There are effects of greatly improving the sensitivity, accuracy, and reproducibility of detection by increasing specificity of binding to a target substance and amplifying a detec...

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Bibliographic Details
Main Authors JUNG HUN KIM, TAI SUN KIM, KEUM SOO SONG
Format Patent
LanguageEnglish
Korean
Published 14.07.2022
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The present invention relates to a nanoparticle conjugate and a method for detecting a target substance using the same. There are effects of greatly improving the sensitivity, accuracy, and reproducibility of detection by increasing specificity of binding to a target substance and amplifying a detection signal. The nanoparticle conjugate may include nanoparticles and DNA fragments bound to the nanoparticles; and antibodies and DNA fragments bound to the antibodies, wherein, in a nanoparticle-DNA conjugate and an antibody-DNA conjugate, each DNA fragments are complementary to each other. 본 발명은 나노입자 컨쥬게이트, 이를 이용한 표적물질 검출방법에 관한 것으로, 표적물질과의 결합 특이도를 높이고, 검출 신호를 증폭시켜, 검출의 민감도, 정확성 및 재현성을 크게 향상시키는 효과가 있다.
Bibliography:Application Number: KR20210115294