SPM138 Novel Pediococcus acidilactici SPM138 having antimicrobial activity against Clostridium difficile and composition comprising the same

• Main Authors: SUNGSOOK CHOI, MINKYUNG CHOI
• Format: Patent
• Language: English; Korean
• Published: 10.06.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FODDER; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The present invention relates to a Pediococcus acidilactici SPM138 strain having antibacterial activity; an antibacterial composition against Clostridium difficile, comprising the strain or a culture thereof as an effective component; a probiotics composition; a pharmaceutical composition for preventing or treating colitis, comprising the strain or the culture thereof as an effective component; a food composition for preventing or alleviating colitis; and a feed additive composition, feed, and an anti-inflammatory composition. The Pediococcus acidilactici SPM138 strain of the present invention or the culture thereof shows a significantly superior antibacterial activity against Clostridium difficile, and thus can be usefully utilized in an antibacterial composition, a probiotics composition, a feed additive composition, or the like, comprising the strain or the culture thereof. 본 발명은 항균 활성을 갖는 페디오코쿠스 에시디락티시() SPM138 균주; 상기 균주 또는 이의 배양물을 유효성분으로 포함하는, 클로스트리듐 디피실()에 대한 항균용 조성물; 프로바이오틱스 조성물; 상기 균주 또는 이의 배양물을 유효성분으로 포함하는, 대장염의 예방 또는 치료용 약학 조성물; 대장염의 예방 또는 개선용 식품 조성물; 사료 첨가용 조성물, 사료 및 항염용 조성물에 관한 것이다. 본 발명의 페디오코쿠스 에시디락티시 SPM138 균주 또는 이의 배양물은 클로스트리듐 디피실에 대해 현저히 우수한 항균 활성을 나타내는바, 이를 포함하는 항균용 조성물, 프로바이오틱스 조성물, 사료 첨가용 조성물 등에 유용하게 활용될 수 있다.