A composition for preventing or treating Porcine reproductive and respiratory syndrome comprising an Ampelopsis brevipedunculata extract a fraction thereof or a compound isolated therefrom

• Main Authors: KWON HYUNG JUN, SU JIN PARK, BYEOUNG SEOB OH, WOO SONG LEE, HYUNG JAE JEONG, YOUNG BAE RYU, MUN CHUAL RHO, JU HUCK LEE, SEUNG WOONG LEE
• Format: Patent
• Language: English; Korean
• Published: 12.03.2019
• Subjects: FODDER; FOODS OR FOODSTUFFS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

A pharmaceutical composition for preventing or treating porcine reproductive and respiratory syndrome (PRRS) comprising an Ampelopsis brevipedunculata extract, a fraction thereof, a compound represented by chemical formula 1, 2, or 11, or a pharmaceutically acceptable salt of the compound, is administered to an individual suspected of PRRS, thereby exhibiting helicase activity inhibition of virus inducing PRRS and/or inhibition of proliferation of the virus. 개머루덩굴() 추출물, 이의 분획물, 이들로부터 분리한 화학식 1, 2, 또는 11으로 표시되는 화합물, 또는 상기 화합물의 약학적으로 허용가능한 염을 유효성분으로 포함하는, 돼지생식기호흡기증후군 (PRRS; Porcine reproductive and respiratory syndrome)의 예방 또는 치료용 약학적 조성물은 돼지생식기호흡기증후군 의심 개체에 투여되어, 돼지생식기호흡기증후군을 유발하는 바이러스의 헬리카아제(Helicase) 활성 저해 및/또는 상기 바이러스의 증식 저해를 나타낼 수 있다.