Method for improving skin whitening effect of Luteolin by irradiation and composition for skin whitening comprising irradiated Luteolin as an active ingredient

• Main Authors: CHOI, DAE SEONG, JEON, JONG HO, JANG, BEOM SU, LEE, DONG EUN, BYUN, EUI BAEK, SONG, HA YEON, KIM, HYE MIN
• Format: Patent
• Language: English; Korean
• Published: 20.12.2018
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

The present invention relates to a method for improving skin whitening activity by emitting radiation to luteolin and a skin whitening composition comprising a radiation emission product of luteolin as an active ingredient and, more specifically, to a manufacturing method of a radiation emission product of luteolin with improved skin whitening activity which comprises a step of emitting radiation to luteolin, a skin whitening cosmetic composition comprising a radiation emission product of luteolin with improved skin whitening activity as an active ingredient, and a pharmaceutical composition for preventing or treating skin pigmentation diseases. The active ingredient is a compound represented by chemical formula 1. 본 발명은 루테올린에 방사선을 조사하여 피부 미백 활성을 향상시키는 방법 및 루테올린의 방사선 조사 산물을 유효 성분으로 포함하는 피부 미백 조성물에 관한 것으로, 보다 상세하게는 루테올린에 방사선을 조사하는 단계를 포함하는, 피부 미백 활성이 향상된 루테올린 방사선 조사 산물의 제조 방법, 피부 미백 활성이 향상된 루테올린 방사선 조사 산물을 유효 성분으로 포함하는, 피부 미백용 화장료 조성물 및 피부 색소 침착 질환 예방 또는 치료용 약학 조성물에 관한 것으로, 상기 유효 성분은 하기 화학식 I로 표시되는 화합물이다.[화학식 I]