GLYCOSAMINOGLYCANS DERIVED FROM INSECT AND A PROCESS FOR PURIFICATION OF THE SAME

Glycosaminoglycans derived from insect are provided to maintain the systolic blood pressure be normal level in a hypertension patient by reducing blood pressure, regulate excessive growth of vascular endothelial cell and inhibit inflammation without excess of heart and pulse pressure. A method for p...

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Bibliographic Details
Main Authors JI, SANG DEOK, HWANG, JAE SAM, YUN, EUN YOUNG, KIM, YEONG SHIK, AHN, MI YOUNG
Format Patent
LanguageEnglish
Published 25.07.2008
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
SPIRITS
VINEGAR
WINE
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Summary:Glycosaminoglycans derived from insect are provided to maintain the systolic blood pressure be normal level in a hypertension patient by reducing blood pressure, regulate excessive growth of vascular endothelial cell and inhibit inflammation without excess of heart and pulse pressure. A method for producing glycosaminoglycans derived from insect comprises the steps of: (1) dipping a dried insect in an organic solvent selected from acetone, hexane, ethylacetate, methylalcohol, ethylalcohol, propanol, butanol, acetonitrile and dichloromethane to remove lipids and drying it; (2) degrading the dried insect of step (1) with alcalase in sodium bicarbonate solution(pH 9.0); (3) removing degraded proteins with 5 wt.% of trichloroacetic acid(TCA), and precipitating the protein removed solution with ethanol, cetylpyridinium and ethanol, sequentially; and (4) dialyzing the precipitates produced from the step (3) with distilled water.
Bibliography:Application Number: KR20070020818