MATRIX TYPED ALGESIC ANTI-INFLAMMATORY AGENT FOR TRANSDERMAL ADMINISTRATION CONTAINING DICLOFENAC

PURPOSE: A matrix typed algesic anti-inflammatory agent for transdermal administration containing Diclofenac is provided, thereby improving its skin-penetration and adhesion and decreasing time for its producing. CONSTITUTION: The matrix typed algesic anti-inflammatory agent for transdermal administ...

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Main Authors YOON, HYE JEONG, SONG, JIN DEOK, CHOI, YEONG GWON, PARK, CHEOL MIN, SIM, YONG HO, LEE, HEON HAN
Format Patent
LanguageEnglish
Korean
Published 30.11.2001
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PURPOSE: A matrix typed algesic anti-inflammatory agent for transdermal administration containing Diclofenac is provided, thereby improving its skin-penetration and adhesion and decreasing time for its producing. CONSTITUTION: The matrix typed algesic anti-inflammatory agent for transdermal administration comprises a backing film which protects a drug; a matrix film containing an active drug; and a release liner film which is removed from the agent prior to using, in which the matrix film contains 1 to 25 wt.% of Diclofenac diethylammonium salt; 40 to 95 wt.% of water-insoluble acryl macromolecule as an adhesive component; 0.1 to 20 wt.% of nonionic surfactant selected from glyceryl monooleate, glyceryl monolaurate and sorbitan monooleate; 0.1 to 10 wt.% of menthol; and 0.1 to 10 wt.% of dissolution assistant selected from triacetin, isopropyl alcohol and propylene glycol, in which the water-insoluble acryl macromolecule is a monopolymer or a copolymer selected from 2-ethylhexyl acrylate, vinyl acrylate and vinyl acrylic acid.
Bibliography:Application Number: KR19980036559