ORAL COMPOSITIONS CONTAINIG DIMETHICONE COPOLYOLS

• Main Author: HUGHES, IAIN ALLAN
• Format: Patent
• Language: English; Korean
• Published: 01.04.2000
• Edition: 7
• Subjects: CHEMISTRY; CHEWING GUM; COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; CONFECTIONERY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; ICE-CREAM; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; PREPARATION THEREOF; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; THEIR PREPARATION OR CHEMICAL WORKING-UP; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

본 발명은 향미제, 생리적 냉각제 및 항균성 화합물으로부터 선택되는 친유성 화합물 그리고 하기 화학식(I)의 알킬- 및 알콕시-디메티콘 코폴리올로부터 선택되는 디메티콘 코폴리올을 포함하는 크림 치약, 분말, 액상 치약, 양치질약, 의치 청정제, 츄잉검 또는 캔디 형태의 구강용 조성물에 관한 것이다. [화학식 1] {여기서, X는 수소, 알킬, 알콕시 및 아실시(약 1 내지 약 16개의 탄소 원자를 가짐)로부터 선택되고, Y는 알킬 및 알콕시기(약 8 내지 약 22개의 탄소 원자를 가짐)로부터 선택되고, n은 약 0 내지 약 200이고, m은 약 1 내지 약 40이고, q는 약 1 내지 약 100이고, 잔기 (CHO-)(CHO-)X의 분자량은 약 50 내지 약 2000이고, x 및 y는 옥시에틸렌 : 옥시프로필렌의 중량비가 약 100:0 내지 약 0:100이다}. 본 조성물은 치아 또는 의치에 대해 친유성 성분의 향상된 실재성, 효력 및/또는 효능과 함께 개선된 안티플라크 및 항박테리아 활성을 제공한다. An oral composition in the form of a toothpaste, powder, liquid dentifrice, mouthwash, denture cleanser, chewing gum or candy comprising a lipophilic compound selected from flavorants, physiological cooling agents and antimicrobial compounds and a dimethicone copolyol selected from alkyl- and alkoxy-dimethicone copolyols having formula (I) wherein X is selected from hydrogen, alkyl, alkoxy and acyl groups having from about 1 to about 16 carbon atoms, Y is selected from alkyl and alkoxy groups having from about 8 to about 22 carbon atoms, n is from about 0 to about 200, m is from about 1 to about 40, q is from about 1 to about 100, the molecular weight of the residue (C2H4O-)x(C3H6O-)yX is from about 50 to about 2000, and x and y are such that the weight ratio of oxyethylene:oxypropylene is from about 100:0 to about 0:100. The composition provides improved antiplaque and anti-bacterial activity together with enhanced substantivity, impact and/or efficacy of the lipophilic components on teeth or dentures.