ACTIVE OXYGEN INHIBITOR

• Main Authors: CHIHIRO, MASATOSHI, KOMATSU, HAJIME, TOMINAGA, MICHIAKI, YABUUCHI, YOUICHI
• Format: Patent
• Language: English; Korean
• Published: 15.06.1999
• Edition: 6
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; DERIVATIVES THEREOF; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SUGARS

하기 일반식 (1) : [식중, R은 페닐환상에 치환기로서 저급 알콕시기를 1 ∼ 3개 가질 수 있는 페닐기, 저급 알킬렌 옥시기를 갖는 페닐기 등을 나타내고; R는 수소원자, 페닐기, 할로겐원자, 저급 알콕시 카르보닐기, 저급 알킬기, 치환기로서 저급알킬기를 가질 수 있는 아미노 - 저급 알킬기 또는 디히드로 카르보스티릴기 등을 나타내며; R은 하기식의 기를 나타내고 (R는 수산기, 카르복시기, 저급 알케닐기, 또는 저급 알킬기를 나타내고, m 은 0, 1 또는 2 를 나타낸다) ; X 는 황원자 또는 산소원자를 나타낸다]로 표시되는 아졸유도체 또는 그의 염을 유효성분으로서 함유하는 활성 산소 억제제. A superoxide radical inhibitor containing, as an effective ingredient, an azole derivative represented by the general formula (1), Äwherein R represents a phenyl group which may have 1-3 lower alkoxy groups as substituent(s) on the phenyl ring, a phenyl group having a lower alkylenedioxy group, or the like; R represents a hydrogen atom, a phenyl group, a halogen atom, a lower alkoxycarbonyl group, a lower alkyl group, an amino-lower alkyl group which may have a lower alkyl group as a substituent, a dihydrocarbostyril group, or the like; R represents a group of the formula, (R represents a hydroxyl group, a carboxy group, a lower alkenyl group or a lower alkyl group. m represents 0, 1 or 2); X represents a sulfur atom : Ü or a salt thereof.