SUBSTITUTED N-(INDOLE-2-CARBONYL)-GLYCINAMIDES AND THEIR DERIVATIVES AS A DIABETIC AGENTS

본 발명은 당뇨병 치료제로서 유용한 특정한 인돌-2-카복스아미드에 관한 것이다. PCT No. PCT/IB95/00442 Sec. 371 Date Dec. 2, 1997 Sec. 102(e) Date Dec. 2, 1997 PCT Filed Jun. 6, 1995 PCT Pub. No. WO96/39384 PCT Pub. Date Dec. 12, 1996Compounds of Formula (1) wherein R6 is carboxy, (C1-C8)alkoxycarbonyl, benzyloxycarbonyl, C(O)NR8R9 o...

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Bibliographic Details
Main Authors HULIN, BERNARD, HOOVER, DENNIS JAY, TREADWAY, JUDITH L, MARTIN, WILLIAM H, PHILLIPS, DOUGLAS
Format Patent
LanguageEnglish
Korean
Published 15.06.1999
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:본 발명은 당뇨병 치료제로서 유용한 특정한 인돌-2-카복스아미드에 관한 것이다. PCT No. PCT/IB95/00442 Sec. 371 Date Dec. 2, 1997 Sec. 102(e) Date Dec. 2, 1997 PCT Filed Jun. 6, 1995 PCT Pub. No. WO96/39384 PCT Pub. Date Dec. 12, 1996Compounds of Formula (1) wherein R6 is carboxy, (C1-C8)alkoxycarbonyl, benzyloxycarbonyl, C(O)NR8R9 or C(O)R12 as glucogen phosphorylase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat diabetes, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemia, hyperlipidemia, atherosclerosis and myocardial ischemia in mammals.
Bibliography:Application Number: KR19960019379