PYRIDINE DERIVATIVES

Pyridine derivatives of formula their heteroaromatic N-oxides and their pharmaceutically acceptable acid addition salts are disclosed. In the formula z is 0,1 and 2 and R,R ,R and R have specified meanings. The compounds exhibit activity as 5-HT1A agonists, antagonists or partial agonists and are us...

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Bibliographic Details
Main Authors MANSELL, HOWARD L, CLIFFE, IAN A, WHITE, ALAN C, TODD, RICHARD S
Format Patent
LanguageEnglish
Korean
Published 16.11.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Pyridine derivatives of formula their heteroaromatic N-oxides and their pharmaceutically acceptable acid addition salts are disclosed. In the formula z is 0,1 and 2 and R,R ,R and R have specified meanings. The compounds exhibit activity as 5-HT1A agonists, antagonists or partial agonists and are useful for the treatment of CNS disorders eg anxiety, as antihypertensives and in treating anorexia.
Bibliography:Application Number: KR19900004697