N-HYDROXY-DIBENZ[B,E]OXEPIN-ALKYLAMINES AND ALKANOIC ACID AMIDES, RELATED HETEROCYCLIC ANALOGUES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS

This invention relates to N-hydroxy-dibenz[b,e]oxepinalkylamines, N-hydroxy-dibenz[b,e]oxepinalkanoic acid amides and related heterocyclic analogues of the formula where X together with the carbon atoms to which it is attached forms a benzene or thiophene ring; W and Z are independently hydrogen, ha...

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Bibliographic Details
Main Authors HAMER, RUSSELL RICHARD LEE, MARTIN, LAWRENCE LEO, ALLEN, RICHARD C, HELSLEY, GROVER CLEVELAND, FREED, BRIAN S, WHITE, JOHN I
Format Patent
LanguageEnglish
Korean
Published 01.10.1999
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to N-hydroxy-dibenz[b,e]oxepinalkylamines, N-hydroxy-dibenz[b,e]oxepinalkanoic acid amides and related heterocyclic analogues of the formula where X together with the carbon atoms to which it is attached forms a benzene or thiophene ring; W and Z are independently hydrogen, halogen, loweralkyl, or trifluoromethyl, R is hydrogen, loweralkyl, or acyl; R is hydrogen, loweralkyl, cycloalkyl, arylloweralkyl or acyl; m is 0 or 1 and n is an integer of 0 to 12 and the pharmaceutically acceptable salts thereof. The compounds of this invention exhibit dermatological and analgesic activity.
Bibliography:Application Number: KR19900013079