NOVEL PYRIMIDINE THIONE COMPOUND AND PROCESS FOR ITS PREPARATION

This invention relates to 2-amino-1-substituted-cycloalka prymidine-4-thione derivative represented by the general formula where R is substituted or unsubstituted amino, C1-C4 alkyl or C3-C7 cycloalkyl, and n denotes from 2 to 7. This compound is synthesized from initial substance (IV) according to...

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Bibliographic Details
Main Authors BANG, CHAN-SIK, WOO, YOUNG-MIN, KIM, JONGAN, LEE, BOK-MAN, YANG, DUK-HO, NAM, KI-PYUNG, KIM, YONG-JOO, KIM, SAM-SIK, OK, JONG-HWA, YEO, JAE-HONY, KIM, SUNG-KYUN
Format Patent
LanguageEnglish
Korean
Published 01.04.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:This invention relates to 2-amino-1-substituted-cycloalka prymidine-4-thione derivative represented by the general formula where R is substituted or unsubstituted amino, C1-C4 alkyl or C3-C7 cycloalkyl, and n denotes from 2 to 7. This compound is synthesized from initial substance (IV) according to the following reactions: halogenation, akylation, substitution with an alkali metal hydrosulfide. This compound is useful as an intermediate of cephalosporin antibiotics. 본 발명은 세팔로스포린계 항생제의 중간체로서 유용한 하기 일반식(Ⅰ)로 표시되는 신규의 2-아미노-1-치환-시클로알카피리미딘-4-티온 유도체를 제공한다. 상기식에서, R은 치환 또는 비치환된 아미노기, C알킬기 또는 C시클로 알킬기를 나타내고, n은 2 내지 7이다.
Bibliography:Application Number: KR19920024739