MANUFACTURE OF INTERMEDIATE FOR LEUKOTRIENE ANTAGONIST

1,3-Dialkoxybenzenes are acylated and deprotected in a mixture of acetic or propionic acid and hydrobromic acid. The dihydroxyphenones thus produced are intermediates in the synthesis of leukotriene antagonists.

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Bibliographic Details
Main Authors UINSUTON SUTANREI MAASHIYARU, SANDORA KEI SHIGUMANDO, SERIA AN HOITSUTOSHITSUTO
Format Patent
LanguageEnglish
Published 20.01.1989
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:1,3-Dialkoxybenzenes are acylated and deprotected in a mixture of acetic or propionic acid and hydrobromic acid. The dihydroxyphenones thus produced are intermediates in the synthesis of leukotriene antagonists.
Bibliography:Application Number: JP19880151065