2-LOWER ALKANOYLOXYPROPANE DERIVATIVE

NEW MATERIAL:A 2-lower alkanoyloxy-3-(N-octadecylcarbamoyloxy)propyl 2-trimethylammonioethyl phosphate or a salt thereof. EXAMPLE:2-(Acetoxy)-3-(N-octadecylcarbamoyloxy) propyl 2-trimethylammonio ethyl phosphate. USE:An antitumor agent having low side effects such as blood platelet aggregation actio...

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Bibliographic Details
Main Authors INOUE KEIZO, OKUYA TETSUYA, NOMURA MASAAKI
Format Patent
LanguageEnglish
Published 07.12.1987
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:NEW MATERIAL:A 2-lower alkanoyloxy-3-(N-octadecylcarbamoyloxy)propyl 2-trimethylammonioethyl phosphate or a salt thereof. EXAMPLE:2-(Acetoxy)-3-(N-octadecylcarbamoyloxy) propyl 2-trimethylammonio ethyl phosphate. USE:An antitumor agent having low side effects such as blood platelet aggregation action, antihypertensive action, permeability action, tissue damaging action, etc. PREPARATION:For example, a compound shown by the formula is prepared and reacted with a compound shown by the formula (RCO)2O (R is 1-3C alkyl) in an inert solvent under an anhydrous condition.
Bibliography:Application Number: JP19860166500