PRODUCTION OF ALCOHOL

• Main Authors: SAITOU KENJI, YAMACHIKA HIROSHI, TAKIZAWA YUKIHISA, KOUNO NOBUHARU
• Format: Patent
• Language: English
• Published: 04.05.1985
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL METHODS OF ORGANIC CHEMISTRY; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE; THEIR RELEVANT APPARATUS; TRANSPORTING

PURPOSE:To produce an alcohol having triple bond, by reacting Mg with a carbonyl compound or oxirane compound and a halogenated propargyl compound at the same time in the presence of metallic zinc or zinc halide in an inert solvent, and hydrolyzing the reaction product. CONSTITUTION:(A) The compound of formula I (R1 and R2 are 1-14C alkyl, alkenyl, alkynyl, phenyl, benzyl, thienyl, etc.; one of R1 and R2 may be H) or the compound of formula II (R3 is H, 1-6C alkyl or phenyl) and (B) the compound of formula III (R4 is H or CH3; X is halogen) are made to react with Mg in an inert solvent (preferably THF) in the presence of metallic zinc or zinc halide (0.05-0.5mol per 1mol of the compound of formula I or formula II), and the reaction product is hydrolyzed to obtain the objective compound of formula IVor formula V. EFFECT:The objective compound can be produced in high yield without using particular apparatus. USE:Intermediate of agricultural chemicals, pharmaceuticals or perfumery.