ALPHA-AMINO ACID, ITS DERIVATIVE, AND THEIR PREPARATION

• Main Authors: FUJITA YOSHIJI, SHIONO MANZOU, NISHIDA TAKUJI
• Format: Patent
• Language: English
• Published: 07.01.1985
• Subjects: ADHESIVES; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; DYES; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HETEROCYCLIC COMPOUNDS; MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE; METALLURGY; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; NATURAL RESINS; ORGANIC CHEMISTRY; PAINTS; POLISHES; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

NEW MATERIAL:A compound shown by the formula I (R is H, or lower alkyl; R and R are H, lower alkyl, lower alkoxy, or R and R are linked to form -CH=CH-CH=CH-; R is H, or protecting group; n is 0-2). EXAMPLE:beta-( 2,3-Dihydro-6-hydroxy- 2,5,7,8-tetramethyl-2H-benzopyranyl )alanine hydrochloride. USE:An antioxidant. Showing improved activity than vitamin E, also useful as an intermediate for synthesizing an antioxidant. PREPARATION:An aldehyde shown by the formula II is reacted with ammonium carbonate and an alkali metal cyanide to give a hydantoin shown by the formula III, which is hydrolyzed to give a compound shown by the formula I .