NOVEL SF-2259 SUBSTANCE AND ITS PREPARATION

PURPOSE:To prepare the titled substance useful for the prevention and remedy of dental caries, by culturing a microbial strain belonging to Micromonospora genus and capable of producing the titled substance. CONSTITUTION:A microbial strain belonging to Micromonospora genus and capable of producing t...

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Main Authors HIDAKA HIDEMASA, TAKIZAWA TOSHIO, SHIYOUMURA TAKASHI, ITOU TATSUO, MATSUHASHI NOBUO, YOSHIDA JIYUNKO
Format Patent
LanguageEnglish
Published 13.09.1984
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Summary:PURPOSE:To prepare the titled substance useful for the prevention and remedy of dental caries, by culturing a microbial strain belonging to Micromonospora genus and capable of producing the titled substance. CONSTITUTION:A microbial strain belonging to Micromonospora genus and capable of producing the novel physiologically active substance, SF-2259, e.g. Micromonospora sp. SF-2259 (FERM-P No.6953), is cultured, and the objective novel physiologically active substance SF-2259 is separated from the cultured product. The substance suppresses the activity of glucosyl transferase produced by Streptococcus mutans, the synthesis of dextran polysaccharide, and the formation of bactrial plague, and accordingly, it is effective to prevent or cure the dental caries.
Bibliography:Application Number: JP19830036637