KALLIKREIN PREPARATION FOR APPLICATION TO ORAL MUCOSA

PURPOSE:To prepare the titled preparation absorbable through the oral mucosa in high efficiency, by adding kallikrein to a specific polymer matrix such as poly (lower alkylene) glycol, PVA, etc. CONSTITUTION:Kallikrein is added to a polymer matrix (preferably having a molecular weight of >=2,000)...

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Main Authors TANAKA MASAKAZU, TOKUNAGA KEIKO, UNUMA TSUNEO, NAITOU SHIYUNICHI, MURAYAMA TAKESHI, HIROSE KATSUMI, MANNEN NARIYASU
Format Patent
LanguageEnglish
Published 26.06.1984
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract PURPOSE:To prepare the titled preparation absorbable through the oral mucosa in high efficiency, by adding kallikrein to a specific polymer matrix such as poly (lower alkylene) glycol, PVA, etc. CONSTITUTION:Kallikrein is added to a polymer matrix (preferably having a molecular weight of >=2,000) selected from poly (lower alkylene) glycol (especially polyethylene glycol), PVA, polyacrylamide or its substituted product (especially polymethacrylamide), poly-N-vinylpyrrolidone, a cellulose ether (especially methylcellulose, hydroxyethylcellulose, etc.), starch and partially etherified starch. The preparation can be administered easily without necessitating complex processes such as conversion to enteric tablet, double-layered tablet containing surface active agent, etc.
AbstractList PURPOSE:To prepare the titled preparation absorbable through the oral mucosa in high efficiency, by adding kallikrein to a specific polymer matrix such as poly (lower alkylene) glycol, PVA, etc. CONSTITUTION:Kallikrein is added to a polymer matrix (preferably having a molecular weight of >=2,000) selected from poly (lower alkylene) glycol (especially polyethylene glycol), PVA, polyacrylamide or its substituted product (especially polymethacrylamide), poly-N-vinylpyrrolidone, a cellulose ether (especially methylcellulose, hydroxyethylcellulose, etc.), starch and partially etherified starch. The preparation can be administered easily without necessitating complex processes such as conversion to enteric tablet, double-layered tablet containing surface active agent, etc.
Author TOKUNAGA KEIKO
MURAYAMA TAKESHI
UNUMA TSUNEO
NAITOU SHIYUNICHI
MANNEN NARIYASU
TANAKA MASAKAZU
HIROSE KATSUMI
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– fullname: NAITOU SHIYUNICHI
– fullname: MURAYAMA TAKESHI
– fullname: HIROSE KATSUMI
– fullname: MANNEN NARIYASU
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Snippet PURPOSE:To prepare the titled preparation absorbable through the oral mucosa in high efficiency, by adding kallikrein to a specific polymer matrix such as poly...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title KALLIKREIN PREPARATION FOR APPLICATION TO ORAL MUCOSA
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