PREPARATION OF 2,3-DIHALOGENOPROPIONITRILE

• Main Authors: KATOU TOSHIO, NAGAI SHIYOUSUKE, YAMAGUCHI TERUHIRO, HIGUCHI CHIYOUJIROU, KAWASHIMA NOBUYUKI, TAKANO TAKAO, MITA RIYUUICHI
• Format: Patent
• Language: English
• Published: 19.04.1982
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL METHODS OF ORGANIC CHEMISTRY; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE; THEIR RELEVANT APPARATUS; TRANSPORTING

PURPOSE:To obtain the titled compound in high yield useful as a raw material for high polymer compounds and a raw material for a physiologically active substance, e.g., drugs, by halogenating directly acrylonitrile with a halogenating agent in the presence of a catalytic amount of an alkali metal halide. CONSTITUTION:Acrylonitrile is halogenated in the presence of an alkali metal halide (e.g., LiF, NaF, KF, etc.) in a molar ratio of the alkali halide to acrylonitrile of 0.05-2mol at -70-70 deg.C, preferably at -20-40 deg.C, to give 2, 3-dihalogenopropionitrile. The reaction is required to undergo at least under scattered light (e.g., natural light passed through glass, scattered light of luminescent lamp). A polymerization inhibitor (e.g., hydroquinone, phenyl-beta-naphthylamine, etc.) may be added preferably.