SOLUTION FOR EXTERNAL USE

PURPOSE:A solution for external use that is prepared by adding dibenzylidene solbitol to a solution contaning an anti-inflammatory analgesic in a solvent of water, a lower alcohol, further preferably a dihydric alcohol, thus continuing the effect of the active ingredient and giving a comfortable fee...

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Bibliographic Details
Main Authors TOMINAGA ANRI, YASUMASU NOBUO, ASANO SHIYUUICHI
Format Patent
LanguageEnglish
Published 18.12.1982
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PURPOSE:A solution for external use that is prepared by adding dibenzylidene solbitol to a solution contaning an anti-inflammatory analgesic in a solvent of water, a lower alcohol, further preferably a dihydric alcohol, thus continuing the effect of the active ingredient and giving a comfortable feel, when applied. CONSTITUTION:An active ingredient, such as anti-inflammatory analgesic, e.g. methyl salicylate, is dissolved in a solvent consisting of water, a lower alcohol such as ethanol or isoprapanol and, preferably a dihydric alcohol such as propylene glycol, at a weight ratio of (5-15):(90-65):(5-15). Then, dibenzylidene sorbitol is added to the above composition by 0.05-1w/v% to give the objecctive solution for external use. This solution forms a gel, when applied on a skin and the lower alcohol evaporates up, gives comfortable feefing without sticking. Further the solution is fast effective and keeps durable effect. The solution contains a film-forming macromolecular compound by 0.1-10w/v% based on the total solution.
Bibliography:Application Number: JP19810090636