PRODUCTION OF INDOLE-3-GLYCEROL

PURPOSE:A microorganism belonging to the genus Corynebacterium, capable of producing the titled compound, is cultured in a medium contaning indole to accumulate the titled compound and the compound is collected readily. CONSTITUTION:A bacterium belonging to the genus Corynebacterium, capable of prod...

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Bibliographic Details
Main Authors KOIWA SHIGEJI, TAKEMOTO HISAO, MATSUSHITA NOBORU
Format Patent
LanguageEnglish
Published 30.11.1982
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:PURPOSE:A microorganism belonging to the genus Corynebacterium, capable of producing the titled compound, is cultured in a medium contaning indole to accumulate the titled compound and the compound is collected readily. CONSTITUTION:A bacterium belonging to the genus Corynebacterium, capable of producing indole-3-glycerol, such as Corynebacterium acetophilum TS-2002 (FERM-5824) is cultured in a medium containing indole to accumulate inodle-3- glycerol, then the compound is collected. This bacterium producing indole-3- glycerol needs tyrosine and/or phenylalanine, when growing and has resistance to triptophane analogs. Indole-3-glycerol has an activity of activating the enzyme synthesizing triptophane and a physiological activity as a member of indole alkaloids, thus being used as medicaments, reagents, industrial chemicals or their intermediate.
Bibliography:Application Number: JP19810076479