5-CYANO-2-SULFONYLPYRIDINE AND ITS PRODUCTION

PROBLEM TO BE SOLVED: To obtain 5-cyano-2-sulfonylpyridine useful as a synthetic intermediate of a pyridine compound as a starting material of a medicine or an agrochemical. SOLUTION: This 5-cyano-2-sulfonylpyridine is expressed by the formula I [R is an alkyl, a cycloalkyl, a (substituted) aryl, et...

Full description

Saved in:
Bibliographic Details
Main Authors SHIONO MANZO, HAMAZAKI TAKASHI, KUWAYAMA TOMOYA, ASANUMA GORO
Format Patent
LanguageEnglish
Published 07.04.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:PROBLEM TO BE SOLVED: To obtain 5-cyano-2-sulfonylpyridine useful as a synthetic intermediate of a pyridine compound as a starting material of a medicine or an agrochemical. SOLUTION: This 5-cyano-2-sulfonylpyridine is expressed by the formula I [R is an alkyl, a cycloalkyl, a (substituted) aryl, etc.]. The compound of the formula I is obtained by producing 2-alkaliformyl-3-butene nitrile by reacting 3-butene nitrile with a formate in the presence of an alkali metal alcoholate of the formula: R OM (R is an alkyl; M,is an alkali metal), producing a diene compound of the formula II (R is an acyl, an alkyl, etc.) by reacting with an alkylating agent, etc., and reacting a sulfonyl cyanide of the formula: N≡C-SO2 R with the resultant diene compound.
Bibliography:Application Number: JP19960238958