PRODUCTION OF D-ARABITOL

• Main Authors: MOINE DIDIER, DELOBEAU DIDIER
• Format: Patent
• Language: English
• Published: 07.04.1998
• Edition: 6
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; BEER; BIOCHEMISTRY; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; DERIVATIVES THEREOF; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; GENERAL METHODS OF ORGANIC CHEMISTRY; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; SACCHARIDES, OTHER THAN SUCROSE, OBTAINED FROM NATURAL SOURCESOR BY HYDROLYSIS OF NATURALLY OCCURRING DI-, OLIGO- ORPOLYSACCHARIDES; SPIRITS; SUGAR INDUSTRY; SUGARS; THEIR RELEVANT APPARATUS; TRANSPORTING; VINEGAR; WINE

PROBLEM TO BE SOLVED: To provide a method for producing D-arabitol, enabling to obtain the compound useful as an intermediate for synthesizing xylitol from a low cost raw material with a good yield, by hydrolyzing a lactose solution, oxidizing the hydrolysates, decarboxylating the oxidation products, and subsequently catalytically hydrogenating the products. SOLUTION: This method for producing D-arabitol comprises hydrolyzing a lactose solution by a chemical means or with an enzyme, oxidizing the obtained mixture of glucose with galactose with air or oxygen in the presence of a palladium catalyst in an alkaline medium or with a microorganism such as a Gluconobacter oxidizing agent ATCC 19357 or 23773, subjecting the obtained mixture of gluconic acid with galactonic acid to a decarboxylation reaction using hydrogen peroxide, and subsequently catalytically hydrogenating the obtained mixture of D-arabitol with D-lyxose in the presence of Raney nickel, etc.