PHOSPHOROUS ACID AMIDE PHOSPHINE

PROBLEM TO BE SOLVED: To obtain the subject novel compound that is a specific phosphorous amide phosphine and is useful as a ligand for a catalyst that can attain high optical yield in reactions such as enantiomer selective hydrogenation reaction, allyl substitution reaction and the like. SOLUTION:...

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Bibliographic Details
Main Authors SCALONE MICHELANGELO, SCHMID RUDOLF, BURKART WOLFGANG
Format Patent
LanguageEnglish
Published 22.09.1998
Edition6
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
APPARATUS THEREFOR
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
THEIR RELEVANT APPARATUS
TRANSPORTING
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Summary:PROBLEM TO BE SOLVED: To obtain the subject novel compound that is a specific phosphorous amide phosphine and is useful as a ligand for a catalyst that can attain high optical yield in reactions such as enantiomer selective hydrogenation reaction, allyl substitution reaction and the like. SOLUTION: This novel compound is represented by formula I (R is a 2-8C alkyl, a 3-8C cycloalkyl; R is a 1-8C alkyl, a 3-8C cycloalkyl, an aryl; R and R in corporate together with a phosphorus atom to form 9-benzophosphoryl, 9-phosphabicyclo[3.3.1] nonyl; * is the chiral center) and is a (R) or (S) chiral novel phosphorous acid amide phosphine, which is useful as a ligand for a catalyst attaining high optical yield in an enantiomer selective reaction. This compound is prepared by reaction of a compound of formula II with a substituted chlorophosphane represented by the formula: R R PCl in a solvent in the presence of a base.
Bibliography:Application Number: JP19980057602