SYNTHETIC INTERMEDIATE FOR SULFONYLUREA DERIVATIVE

• Main Authors: SUH BYOUNG W, CHOI JONG K, SA JONG S, LEE JAE CHOL, HEO TAE HO, JUNG INN-BAE
• Format: Patent
• Language: English
• Published: 18.08.1998
• Edition: 6
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; APPARATUS THEREFOR; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; FISHING; FORESTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PEST REPELLANTS OR ATTRACTANTS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; THEIR RELEVANT APPARATUS; TRANSPORTING; TRAPPING

PROBLEM TO BE SOLVED: To obtain the subject compound that is useful as a synthetic intermediate for sulfonylurea herbicide by simplified one-step reaction. SOLUTION: Pyridinium-1-(pyrazolylsulfonylamino)carboxylate of formula I (R is H, a 1-4C alkyl or phenyl; R is H, a 1-4C alkyl or phenyl; R is H, methyl, ethyl or phenyl) is obtained by reaction of a sulfonyl chloride derivative of formula II with alkali metal cyanate, preferably sodium cyanate and pyridine in a solvent. The compound of formula I is allowed to react with 2-amino-4,6- dimethoxypyrimidine to give a sulfonylurea derivative of formula III, which is useful as a herbicide. According to this process, this sulfonylurea derivative of high purity can be obtained through a one-step reaction in high yield.