FR198248 SUBSTANCE

PROBLEM TO BE SOLVED: To provide a novel FR198248 substance which is obtained by culturing an Aspergillus microorganism capable of producing the FR198248 substance, has strong medicinal activity, particularly excellent antiviral activity and is useful as an antiviral agent. SOLUTION: This substance...

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Bibliographic Details
Main Authors HASHIMOTO MASAHARU, SAKAMOTO NORITOSHI, TAKASE SHIGEHIRO, NISHIHARA YUTAKA, OTSU REIKO, TSUJII EISAKU, KINO TORU
Format Patent
LanguageEnglish
Published 22.09.1997
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOUNDS OF UNKNOWN CONSTITUTION
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:PROBLEM TO BE SOLVED: To provide a novel FR198248 substance which is obtained by culturing an Aspergillus microorganism capable of producing the FR198248 substance, has strong medicinal activity, particularly excellent antiviral activity and is useful as an antiviral agent. SOLUTION: This substance is acidic, melts at 112-117 deg.C (with decomposition), dissolves in dimethyl sulfoxide and methanol, slightly soluble in water, and insoluble in dichloromethane, in color reactions, positive to cerium sulfate, ferric chloride and iodine vapor but negative to ninhydrin and Molish reactions. This substance has strong medicinal activity, particularly excellent antiviral activity and is useful as an antiviral agent. This novel substance is obtained by culturing a microorganism capable of producing this substance in Aspergillus, for example, Aspergillus terreus No. 13830 strain and collecting its product.
Bibliography:Application Number: JP19960060928