MEASUREMENT OF ACTIVITY OF PHYSIOLOGICALLY ACTIVE SUBSTANCE

PURPOSE: To simply measure the activities of a physiologically active substance specifically in high sensitivity by using a peptide derivative having a certain number of amino acid residues as a substrate for the active substance which acts on peptides or proteins and fractionating the reaction prod...

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Bibliographic Details
Main Authors HAMAZUME YASUKI, IKENAKA TOKUJI, MEGA TOMOHIRO
Format Patent
LanguageEnglish
Published 22.10.1996
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC
GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS
HETEROCYCLIC COMPOUNDS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
TESTING
VINEGAR
WINE
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Summary:PURPOSE: To simply measure the activities of a physiologically active substance specifically in high sensitivity by using a peptide derivative having a certain number of amino acid residues as a substrate for the active substance which acts on peptides or proteins and fractionating the reaction products. CONSTITUTION: A peptide comprising 2-15 amino acids, represented by formula I [A is an amino acid residue or the residue of a peptide comprising a sequence of 2-13 amino acids; A is the N-terminal amino acid residue; A is the C- terminal amino acid residue; R is a fluorescent or UV-absorbing group binding to an NH group; R is OH or a carboxyl-protecting group, the formula: NH-Y-R (R is a fluorescent or UV-absorbing group ; Y is a 1-10C alkylene, phenylene)] or by formula IT is used as a substrate for a physiologically active substance and the products which is formed by the action of the active substance are fractionated and determined to simply know its activity specifically in high sensitivity.
Bibliography:Application Number: JP19960032870