BULB OF EYE PRESERVING SOLUTION FOR CORNEA GRAFT

• Main Authors: YAMAGUCHI TOSHIJIRO, OBARA TAKEO
• Format: Patent
• Language: English
• Published: 19.04.1994
• Edition: 5
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BANDAGES, DRESSINGS OR ABSORBENT PADS; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FISHING; FOMENTATION; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PROSTHESES; TRAPPING; TREATMENT OR PROTECTION OF EYES OR EARS

PURPOSE:To obtain a bulb of eye preserving solution for cornea graft comprising hyaluronic acid, one polymer substance of organism, having high viscoelasticity and extremely high water retention, capable of reducing swelling properties of cornea during storage or its physiologically permissible salt. CONSTITUTION:A bulb of eye preserving solution for cornea graft comprises hyaluronic acid or its physiologically permissible salt (especially preferably one having 50,000-250,000 molecular weight). The amount of hyaluronic acid or its physiologically permissible salt is preferably 0.05-0.5wt/vol.% per preserving solution. The osmotic pressure of the bulb of eye preserving solution for cornea graft is preferably adjusted to 260-350 mOsm. An extracted whole bulb of eye or corneal piece is stored in the preserving solution. The preserving solution has low swelling properties of cornea, has low influence on corneal endothelia cell and is excellent.