JPH0560810B

PURPOSE:To obtain a non-steroidal anti-inflammatory drug for oral administration free from side effect such as ulceration, effective in reducing the size of drug and useful as an analgesic antipyretic agent, by compounding ibuprofen with a specific amount of magnesium stearate. CONSTITUTION:Ibuprofe...

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Bibliographic Details
Main Authors SHIMANO KIMIHIDE, HARASHIMA SAYURI, TAKASHIMA YASUJI, KOYAMA IKUO
Format Patent
LanguageEnglish
Published 03.09.1993
Edition5
Subjects
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Summary:PURPOSE:To obtain a non-steroidal anti-inflammatory drug for oral administration free from side effect such as ulceration, effective in reducing the size of drug and useful as an analgesic antipyretic agent, by compounding ibuprofen with a specific amount of magnesium stearate. CONSTITUTION:Ibuprofen [2-(4-isobutyl)propionic acid] is compounded with 5-100wt%, preferably 10-50wt% magnesium stearate. The composition is formed in the form of e.g. tablet, pill, granule, fine granule, powder, troche, capsule, etc. The magnesium stearate may be an officinal compound (a mixture of magnesium stearate and magnesium palminate containing 3.9-1.5wt% magnesium in dry basis).
Bibliography:Application Number: JP19860135561