PEPTIDE AND ITS SALT

PURPOSE:To provide a new peptide having specific reactivity and high binding performance to diuretic hormone and useful as a treating agent or clinical examination agent for hypertension and circulatory diseases and an inhibitor for the physiological and biochemical investigation of diuretic hormone...

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Bibliographic Details
Main Authors HAYASHI TAKASHI, BABA KENZO, ODAKAWA YASUHISA, WATANABE HIROO, IZUTSU HIROSHI
Format Patent
LanguageEnglish
Published 08.06.1993
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:PURPOSE:To provide a new peptide having specific reactivity and high binding performance to diuretic hormone and useful as a treating agent or clinical examination agent for hypertension and circulatory diseases and an inhibitor for the physiological and biochemical investigation of diuretic hormone. CONSTITUTION:A peptide (e.g. the peptide of formula III) bindable to diuretic hormone and containing a continuous sequence of at least 4 amino acids existing in the amino acid sequence specified by formula I or formula II. The peptide can be produced e.g. by chemical synthesis using a solid-phase process or liquid- phase process or by biological synthesis comprising the preparation of a vector containing a DNA chain capable of coding the peptide, the transformation of a cultured procaryotic cell or eucaryotic cell with the vector and the production of the peptide by the transformant.
Bibliography:Application Number: JP19910295722