JPH0413358B

Propioxatins A and B, which have the formula:wherein R represents a hydrogen atom or a methyl goup, can be prepared by cultivating a suitable strain of Kitasatosporia, e.g. Kitasatosporia sp. SANK 60684 (FERM-P 7581) They can be salified to give pharmaceutically acceptable salts. The compounds are a...

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Bibliographic Details
Main Authors INAOKA YOSHINORI, TAMAOKI HIDETSUNE, ENOKIDA RYUZO, TAKAHASHI HIDEJI
Format Patent
LanguageEnglish
Published 09.03.1992
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOUNDS OF UNKNOWN CONSTITUTION
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Propioxatins A and B, which have the formula:wherein R represents a hydrogen atom or a methyl goup, can be prepared by cultivating a suitable strain of Kitasatosporia, e.g. Kitasatosporia sp. SANK 60684 (FERM-P 7581) They can be salified to give pharmaceutically acceptable salts. The compounds are active as enkephalinase B inhibitors and are thus capable of enhancing enkephalin activity in vivo.
Bibliography:Application Number: JP19840208789