PYRIDINE DERIVATIVE

NEW MATERIAL:The compound of formula I [R and R are lower alkyl or one of R and R is lower alkyl and the other is -A -NR R (A is lower alkylene; R and R are lower alkyl or together form a ring); R and R are lower alkyl or one of R and R is lower alkyl and the other is -A -R (A is lower alkylene; R i...

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Bibliographic Details
Main Authors KOIDE TOKUO, IWAMOTO HIDENORI, IKADAI HIROYUKI, MATSUHISA AKIRA
Format Patent
LanguageEnglish
Published 08.03.1990
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:NEW MATERIAL:The compound of formula I [R and R are lower alkyl or one of R and R is lower alkyl and the other is -A -NR R (A is lower alkylene; R and R are lower alkyl or together form a ring); R and R are lower alkyl or one of R and R is lower alkyl and the other is -A -R (A is lower alkylene; R is di(lower alkyl)amino, etc.); R and R are H, lower alkoxy, etc.; R and R are adjacent to each other and together form a lower alkylenedioxy] and its salt. EXAMPLE:Dimethylaminoethyl methyl 4-[2-(3-methyl)butenyloxycarbonyl-3,4- methylenedioxy-5-methoxy]phenyl-2,6-dimethyl-1,4-dihydropyridine-3,5- dicarboxylate. USE:A preventive and remedy for hepatic diseases. PREPARATION:The compound of formula I can be produced by reacting a compound of formula II with a compound of formula III and, as necessary, oxidizing the product.
Bibliography:Application Number: JP19880223335