JPH0254839B

NEW MATERIAL:The compound of formula I {R is group of formula II [R is (protected) amino] or haloacetyl; A is CH2 or C=N-OR (R is H or 1-8C alkyl); R is OH or OR (R is H or acyl); R is carboxy or its ester; dotted line is 3-cephem or cepham; when R is group of formula I, A is C=N-OR , when R is halo...

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Bibliographic Details
Main Authors TAKASUGI HISASHI, CHIBA TOSHUKI, TAKATANI TAKAO, TSUJI KIRYO
Format Patent
LanguageEnglish
Published 22.11.1990
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:NEW MATERIAL:The compound of formula I {R is group of formula II [R is (protected) amino] or haloacetyl; A is CH2 or C=N-OR (R is H or 1-8C alkyl); R is OH or OR (R is H or acyl); R is carboxy or its ester; dotted line is 3-cephem or cepham; when R is group of formula I, A is C=N-OR , when R is haloacetyl, R is H and dotted line is 3-cephem, when R is group of formula I and R is H, A is C=NOH, and when R is OR , dotted line is cepham] or its salt. EXAMPLE:7-[2-( 2-Aminothiazol-4-yl )-2-methoxyiminoacetamido]-3-hydroxy-3-ce phem-4-carboxy-lic acid 4-nitrobenzyl ester hydrochloride. USE:Antibacterial agent and its intermediate. PREPARATION:The compound of formula III or its reactive derivative is made to react with the compound of formula R ACO2H or its reactive derivative.
Bibliography:Application Number: JP19840182443