抗プログラム細胞死リガンド１（ＰＤ－Ｌ１）抗体

• Format: Patent
• Language: Japanese
• Published: 10.04.2025
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

本発明は、抗ＰＤ－Ｌ１抗原結合分子を提供し、抗体及びその抗原結合断片、ならびに癌を含む様々な疾患を治療するための該抗ＰＤ－Ｌ１抗原結合分子の使用を包含する。 The present invention provides anti-PD-L1 antigen binding molecules, including antibodies and the antigen binding fragment thereof, and methods for using the same for treating a variety of diseases, including cancers. The antibodies may be delivered to a subject within a pharmaceutical composition for treatment of a variety of diseases, including various types of cancers. Administration results in an activated immune system that can then target tumor cells within the subject. Additional therapeutic agents, including other pharmaceuticals, may be administered in conjunction with the molecules of the invention to aid the treatment of the subject.