METHODS FOR TREATMENT OF REFRACTORY GENERALIZED MYASTHENIA GRAVIS

To provide methods of treating refractory generalized myasthenia gravis.SOLUTION: The disclosure provides methods of treating myasthenia gravis (MG) in a subject in need thereof by administering to the subject a substance that specifically binds complement component 5 (C5). In certain embodiments, t...

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Bibliographic Details
Main Authors WANG JING JING, CAMILLE BEDROSIAN, FANNY O'BRIEN
Format Patent
LanguageEnglish
Japanese
Published 06.11.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide methods of treating refractory generalized myasthenia gravis.SOLUTION: The disclosure provides methods of treating myasthenia gravis (MG) in a subject in need thereof by administering to the subject a substance that specifically binds complement component 5 (C5). In certain embodiments, the substance that specifically binds C5 is a binding protein, such as an anti-C5 antibody.SELECTED DRAWING: None 【課題】難治性全身型重症筋無力症を処置する方法を提供する。【解決手段】本開示は、補体成分５（Ｃ５）に特異的に結合する物質を被験体に投与することにより、それを必要とする被験体において重症筋無力症（ＭＧ）を処置する方法を提供する。特定の実施態様において、Ｃ５に特異的に結合する物質は、抗Ｃ５抗体のような結合タンパク質である。【選択図】なし
Bibliography:Application Number: JP20240134758