METHOD FOR DETECTING RISK OF DRUG-RESISTANT BACTERIA COLONIZATION, USING BACTERIAL FLORA

• Main Authors: MORINAGA YOSHITOMO, KAWASUJI HITOSHI, YAMAMOTO YOSHIHIRO
• Format: Patent
• Language: English; Japanese
• Published: 20.06.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

To detect the risk of drug-resistant bacteria colonization, using bacterial flora.SOLUTION: A method for detecting the risk of drug-resistant bacteria colonization in a subject includes quantifying nucleic acids of one or more bacteria correlated or inversely correlated with the colonization of drug-resistant bacteria in a faces sample collected from the subject, and determining the risk of drug-resistant bacteria colonization based on the levels of nucleic acids measured in the quantification step or an increase/decrease thereof.SELECTED DRAWING: Figure 9 【課題】細菌叢を利用して、薬剤耐性菌の定着リスクを検出すること。【解決手段】被検体における薬剤耐性菌の定着リスクを検出する方法は、被検体から採取した糞便試料から、薬剤耐性菌の定着性と相関又は逆相関の関係がある１又は複数の細菌の核酸を定量すること、及び前記定量する工程で得られた核酸の量又はその増減から、薬剤耐性菌の定着リスクを判定することを含む方法。【選択図】図９