COMPOSITION, COMPRISING TMEM176B OR EXPRESSION OR ACTIVITY REGULATOR THEREOF AS ACTIVE INGREDIENT, FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASE

• Main Authors: PARK SEONGJEONG, KIM HYE JOO, KIM JONG-FUAN, PARK SANG HOON
• Format: Patent
• Language: English; Japanese
• Published: 21.05.2024
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

To provide a composition for prevention or treatment of neurodegenerative brain disease.SOLUTION: Provided is a composition for prevention or treatment of neurodegenerative brain disease, the composition including TMEM176B (Transmembrane Protein 176B), a polynucleotide encoding the same, or an agent for enhancing activity or expression of the TMEM176B or the polynucleotide as an active ingredient.SELECTED DRAWING: Figure 3 【課題】神経変性脳疾患の予防または治療用組成物を提供する。【解決手段】ＴＭＥＭ１７６Ｂ（Ｔｒａｎｓｍｅｍｂｒａｎｅ Ｐｒｏｔｅｉｎ １７６Ｂ）タンパク質、それをコードするポリヌクレオチド、またはそれらの活性または発現増強剤を有効成分として含む、神経変性脳疾患の予防または治療用薬学的組成物とする。【選択図】図３