ANTI-IL-22 ANTIBODY, ANTIBODY FRAGMENT, AND IMMUNOCONJUGATE THEREOF AND USES THEREOF

To provide pharmaceutical compositions and methods for treating autoimmune diseases.SOLUTION: There are provided an anti-IL-22 antibody or antibody fragment that binds to both human IL-22 and a mammalian IL-22 as well as modified anti-IL-22 antibodies and antibody fragments. Pharmaceutical compositi...

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Bibliographic Details
Main Authors JAY M SHORT, CHANG HWAI WEN, WILLIAM BOYLE, FREY GERHARD
Format Patent
LanguageEnglish
Japanese
Published 01.05.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide pharmaceutical compositions and methods for treating autoimmune diseases.SOLUTION: There are provided an anti-IL-22 antibody or antibody fragment that binds to both human IL-22 and a mammalian IL-22 as well as modified anti-IL-22 antibodies and antibody fragments. Pharmaceutical compositions and kits comprising the antibody or antibody fragment are also provided. Also provided are methods for treatment of various IL-22 mediated conditions and diseases.SELECTED DRAWING: None 【課題】自己免疫疾患を治療するための医薬組成物および方法を提供する。【解決手段】ヒトＩＬ－２２および哺乳動物ＩＬ－２２の両方に結合する抗ＩＬ－２２抗体または抗体断片および、改変された抗ＩＬ－２２抗体および抗体断片である。抗体または抗体断片を含む医薬組成物およびキットも提供される。また、種々のＩＬ－２２媒介症状および疾患の治療のための方法も提供される。【選択図】なし
Bibliography:Application Number: JP20240021786