AQUEOUS LIQUID PREPARATION

To provide a formulation technique for providing preservation efficacy to a level where at least bacteriostatic activity is observed without blending a preservative in an aqueous liquid preparation containing brimonidine and/or a salt thereof.SOLUTION: There is provided an aqueous liquid preparation...

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Bibliographic Details
Main Author IEMOTO SUZUKA
Format Patent
LanguageEnglish
Japanese
Published 25.03.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a formulation technique for providing preservation efficacy to a level where at least bacteriostatic activity is observed without blending a preservative in an aqueous liquid preparation containing brimonidine and/or a salt thereof.SOLUTION: There is provided an aqueous liquid preparation containing brimonidine and/or a salt thereof, edetic acid and/or a salt thereof and a buffering agent, which has preservation efficacy to a level where at least bacteriostatic activity is observed even if a preservative is not substantially contained.SELECTED DRAWING: None 【課題】本発明の目的は、ブリモニジン及び／又はその塩を含む水性液剤において、保存剤を配合することなく、少なくとも静菌作用が認められる水準以上の保存効力を備えさせる製剤技術を提供することである。【解決手段】ブリモニジン及び／又はその塩と、エデト酸及び／又はその塩と、緩衝剤とを含む水性液剤は、保存剤を実質的に含まなくても、少なくとも静菌作用が認められる水準の保存効力を備え得る。【選択図】なし
Bibliography:Application Number: JP20240020182