ORAL CARE COMPOSITIONS FOR GUM HEALTH

• Main Authors: CHARLES CARSON BASCOM, MALGORZATA KLUKOWSKA, SHI YUNMING, ROBERT JOSEPH ISFORT, RYAN TASSEFF, STRAND ROSS, AARON REED BIESBROCK
• Format: Patent
• Language: English; Japanese
• Published: 05.03.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

To provide a composition or oral care regimen for a non-surgical treatment to individuals with high risk of developing or currently diagnosed with gum recession.SOLUTION: Provided are an oral care composition with gum health compound, amino acid, and/or mucoadhesive compound; an oral care composition with gum health compound, a pentapeptide, such as palmitoyl KTTKS, and/or a mucoadhesive compound; as well as methods of preventing gingival recession, stopping gingival recession, reversing gingival recession, decrease gum recession, increase gingival barrier protection, promoting collagen synthesis, promoting extracellular matrix synthesis, increasing gum resilience, increasing epidermal thickness, and/or promoting fibrillin synthesis, in an oral cavity of an animal by contacting the oral care compositions with at least one surface of the oral cavity.SELECTED DRAWING: None 【課題】歯肉退縮発症リスクの高い個人、又は現在、歯肉退縮と診断されている個人に対する非外科療法用の組成物及び口腔ケアレジメンを提供する。【解決手段】歯肉健康化合物、アミノ酸、及び／又は粘膜付着性化合物を有する口腔ケア組成物。歯肉健康化合物、パルミトイルＫＴＴＫＳなどのペンタペプチド、及び／又は粘膜付着性化合物を有する口腔ケア組成物。口腔ケア組成物を口腔の少なくとも１つの表面と接触させることによって、動物の口腔内における歯肉退縮の防止、歯肉退縮の停止、歯肉退縮の回復、歯肉退縮の減少、歯肉バリア保護の向上、コラーゲン合成の促進、細胞外マトリックス合成の促進、歯肉の回復力の向上、表皮の厚さの増加、及び／又はフィブリリン合成の促進の方法。【選択図】なし