QUINAZOLINONE AS PARP14 INHIBITOR

To provide a quinazolinone and related compound that are an inhibitor of PARP14 and useful in the treatment of cancer.SOLUTION: For example, the following compounds are shown.SELECTED DRAWING: None 【課題】ＰＡＲＰ１４の阻害剤であり、癌の処置に有用なキナゾリノンおよび関連化合物を提供する。【解決手段】例えば下記の化合物が示される。JPEG2024023224000317.jpg2349JPEG202...

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Bibliographic Details
Main Authors LAURIE B SCHENKEL, KERREN KALAI SWINGER, MELISSA MARIE VASBINDER, KEVIN WAYNE KUNTZ
Format Patent
LanguageEnglish
Japanese
Published 21.02.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a quinazolinone and related compound that are an inhibitor of PARP14 and useful in the treatment of cancer.SOLUTION: For example, the following compounds are shown.SELECTED DRAWING: None 【課題】ＰＡＲＰ１４の阻害剤であり、癌の処置に有用なキナゾリノンおよび関連化合物を提供する。【解決手段】例えば下記の化合物が示される。JPEG2024023224000317.jpg2349JPEG2024023224000318.jpg2344【選択図】なし
Bibliography:Application Number: JP20230188422