2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS

To provide inhibitors of SHP2 and pharmaceutical compositions comprising the same.SOLUTION: For example, a compound of the following formula is illustrated.SELECTED DRAWING: None 【課題】ＳＨＰ２の阻害剤およびそれを含む医薬組成物を提供する。【解決手段】例えば、下記式の化合物が示される。TIFF2024009957000414.tif39101【選択図】なし...

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Main Authors ANDREAS BUCKL, ASHUTOSH JOGALEKAR, ELENA S KOLTUN, KEVIN MELLEM, NAING AAY, CHRISTOPHER SEMKO, GERT KISS, WALTER WON, ADRIAN GILL
Format Patent
LanguageEnglish
Japanese
Published 23.01.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide inhibitors of SHP2 and pharmaceutical compositions comprising the same.SOLUTION: For example, a compound of the following formula is illustrated.SELECTED DRAWING: None 【課題】ＳＨＰ２の阻害剤およびそれを含む医薬組成物を提供する。【解決手段】例えば、下記式の化合物が示される。TIFF2024009957000414.tif39101【選択図】なし
Bibliography:Application Number: JP20230177195