ISTRADEFYLLINE PREPARATION

To provide a novel formulation with improved dissolution properties of istradefylline.SOLUTION: An oral solid preparation according to one embodiment of the present invention comprises: istradefylline or a pharmaceutically acceptable salt thereof; and hydroxypropylcellulose and/or sucrose fatty acid...

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Bibliographic Details
Main Authors OKAMOTO YASUNOBU, HAYASHIDA KAZUKI, SASAKI TAKASHI, KATAYAMA TAKESHI
Format Patent
LanguageEnglish
Japanese
Published 28.12.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:To provide a novel formulation with improved dissolution properties of istradefylline.SOLUTION: An oral solid preparation according to one embodiment of the present invention comprises: istradefylline or a pharmaceutically acceptable salt thereof; and hydroxypropylcellulose and/or sucrose fatty acid ester having a molar substitution degree of 3.SELECTED DRAWING: Figure 3 【課題】イストラデフィリンの溶出性が改善された新規の製剤を提供する。【解決手段】本発明の一態様に係る経口固形製剤は、イストラデフィリンまたはその薬学的に許容される塩と、モル置換度が３のヒドロキシプロピルセルロースおよび／またはショ糖脂肪酸エステルと、を含んでいる。【選択図】図３
Bibliography:Application Number: JP20230190309