C40-, C28-, AND C-32-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS

To provide compounds and compositions that inhibit mTOR, and methods of treating diseases mediated by mTOR.SOLUTION: For example, a specific compound having the following rapamycin skeleton is illustrated.SELECTED DRAWING: None 【課題】ｍＴＯＲを阻害する化合物および組成物、並びにｍＴＯＲにより介在される疾患を処置する方法を提供する。【解決手段】例えば、下記のラパマイシン...

Full description

Saved in:
Bibliographic Details
Main Authors JAMES JOSEPH CREGG, CHRISTOPHER MICHAEL SEMKO, ARUN P THOTTUMKARA, MICAH JAMES EVANS GLIEDT, GERT KISS, ADRIAN LIAM GILL, G LESLIE BURNETT, WALTER WON, WANG GANG, KEVIN T MELLEM, JULIE CHU-LI LEE, JENNIFER PITZEN, JAMES BRADLEY AGGEN
Format Patent
LanguageEnglish
Japanese
Published 26.12.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:To provide compounds and compositions that inhibit mTOR, and methods of treating diseases mediated by mTOR.SOLUTION: For example, a specific compound having the following rapamycin skeleton is illustrated.SELECTED DRAWING: None 【課題】ｍＴＯＲを阻害する化合物および組成物、並びにｍＴＯＲにより介在される疾患を処置する方法を提供する。【解決手段】例えば、下記のラパマイシン骨格を有する特定の化合物が示される。TIFF2023182654000636.tif73146【選択図】なし
Bibliography:Application Number: JP20230164097