METHOD FOR PRODUCING DIARYLPYRIDINE DERIVATIVES
To provide a novel, industrially useful method for producing diarylpyridine derivatives.SOLUTION: The present invention provides a novel method for synthesizing pyridine rings without involving palladium, a strong base, or a high-temperature reaction. In particular, the present invention provides a...
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Main Authors | , , , , |
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Format | Patent |
Language | English Japanese |
Published |
31.10.2023
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Subjects | |
Online Access | Get full text |
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Summary: | To provide a novel, industrially useful method for producing diarylpyridine derivatives.SOLUTION: The present invention provides a novel method for synthesizing pyridine rings without involving palladium, a strong base, or a high-temperature reaction. In particular, the present invention provides a method that can synthesize iminium salts as intermediates, synthesize cyano compounds from these iminium salts, and cyclize the cyano compounds into pyridines under very mild reaction conditions.SELECTED DRAWING: None
【課題】本発明は、ジアリールピリジン誘導体の新規な製造方法に関し、工業的に有用で新規な方法を提供することを目的とする。【解決手段】パラジウム、強塩基、および高温下での反応を用いない、ピリジン環の新規な合成方法を提供する。特に、中間体であるイミニウム塩の合成、イミニウム塩からシアノ化合物への合成、およびピリジンへの環化についても、極めて温和な反応条件で合成できる方法である。【選択図】なし |
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Bibliography: | Application Number: JP20230134392 |