COMPOSITION FOR IMPROVING, TREATING OR PREVENTING MUSCULAR DISORDERS COMPRISING SULFONAMIDE-BASED COMPOUNDS

• Main Authors: PARK JONGSUN, PARK JISOO, LEE HYUNJI
• Format: Patent
• Language: English; Japanese
• Published: 20.10.2023
• Subjects: FODDER; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

To provide a composition for preventing, improving, or treating muscular disorders.SOLUTION: Provided is a pharmaceutical composition for preventing or treating muscular disorders, including sulfonamide-based compounds represented by the formula [1] or pharmaceutically acceptable salts thereof, where R1 represents H, *-(C=N)-NH2, substituted/unsubstituted acetyl, C5-6 aryl or heteroaryl; and R2 represents -NH2 or a substituent represented by the formula [1-1].SELECTED DRAWING: Figure 6 【課題】筋肉疾患予防、改善又は治療用組成物の提供。【解決手段】下記［化１］で表されるスルホンアミド系化合物又はその薬学的に許容可能な塩を含む筋肉疾患予防又は治療用薬学的組成物とする。TIFF2023155212000047.tif40170式中、Ｒ1は、H、＊－（Ｃ＝Ｎ）－ＮＨ２、置換／非置換のアセチル、Ｃ５－６のアリール又はヘテロアリール；Ｒ２は、－ＮＨ２又は下記［化１－１］で表される置換基を表す。TIFF2023155212000048.tif54170【選択図】図６