REAGENT FOR SERINE PROTEASE DETECTION OR MEASUREMENT

To provide a new reagent and method for highly sensitively and precisely detecting or measuring both free and conjugated serine proteases in a sample.SOLUTION: A reagent for detecting or measuring a serine protease that may be present in a living body in the form of a conjugate with a corresponding...

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Bibliographic Details
Main Authors YASHIKI TETSUYA, SONE TAKUYA
Format Patent
LanguageEnglish
Japanese
Published 07.09.2023
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:To provide a new reagent and method for highly sensitively and precisely detecting or measuring both free and conjugated serine proteases in a sample.SOLUTION: A reagent for detecting or measuring a serine protease that may be present in a living body in the form of a conjugate with a corresponding binding molecule, includes the following A and B: (A) surfactant; and (B) an antibody against the serine protease or an antigen-binding fragment thereof.SELECTED DRAWING: None 【課題】試料中の遊離体および結合体の両方のセリンプロテアーゼを、高感度かつ高精度で検出または測定する新たな試薬および方法を提供すること。【解決手段】 対応する結合分子との結合体の形態で生体内に存在し得るセリンプロテアーゼの検出または測定用試薬であって、以下のＡおよびＢ：（Ａ）界面活性剤、（Ｂ）該セリンプロテアーゼに対する抗体またはその抗原結合フラグメントを含む、試薬。【選択図】なし
Bibliography:Application Number: JP20220029580