SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME VIRUS ANTIBODY DETECTION KIT AND SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME VIRUS ANTIBODY DETECTION METHOD

• Main Authors: KIYOKU YASUO, MATSUU AYA, MOMOI YASUYUKI
• Format: Patent
• Language: English; Japanese
• Published: 18.08.2023
• Subjects: CHEMISTRY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; TESTING

To provide a severe fever with thrombocytopenia syndrome virus antibody detection kit and severe fever with thrombocytopenia syndrome virus antibody detection method capable of rapidly and easily detecting IgM and IgG by discrimination.SOLUTION: A severe fever with thrombocytopenia syndrome virus antibody detection kit comprises: labeled recombinant nucleic acid protein of a severe fever with thrombocytopenia syndrome virus; and a chromatographic medium 10 including a sample reaction part to be exposed to a blood sample, and a capture part 31 for capturing an antibody with respect to nucleic acid protein of the severe fever with thrombocytopenia syndrome virus in the blood sample. The capture part 31 includes at least one of an IgM antibody capture part 31a on which an anti-IgM antibody that specifically binds to an IgM antibody as an antibody is immobilized; and an IgG antibody capture part 31b on which an IgG antibody capture molecule that specifically binds to an IgG antibody as an antibody is immobilized.SELECTED DRAWING: Figure 1 【課題】迅速かつ簡便に、ＩｇＭとＩｇＧとを区別して検出することができる重症熱性血小板減少症候群ウイルス抗体検出キット及び重症熱性血小板減少症候群ウイルス抗体検出法を提供する。【解決手段】重症熱性血小板減少症候群ウイルス抗体検出キットは、重症熱性血小板減少症候群ウイルスの標識された組換え核酸タンパク質と、血液検体に暴露される検体反応部、及び血液検体中の重症熱性血小板減少症候群ウイルスの核酸タンパク質に対する抗体を捕捉する捕捉部３１を有するクロマトグラフ媒体１０と、を備える。捕捉部３１は、抗体としてのＩｇＭ抗体と特異的に結合する抗ＩｇＭ抗体が固定化されたＩｇＭ抗体捕捉部３１ａ、及び抗体としてのＩｇＧ抗体と特異的に結合するＩｇＧ抗体捕捉分子が固定化されたＩｇＧ抗体捕捉部３１ｂの少なくとも一方を備える。【選択図】図１