DISEASE/CONSTITUTION ANALYSIS METHOD, DISEASE/CONSTITUTION ANALYSIS SYSTEM, PROGRAM, AND COMPUTER READABLE RECORDING MEDIUM

• Main Author: DAN KATSUAKI
• Format: Patent
• Language: English; Japanese
• Published: 16.08.2023
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; VINEGAR; WINE

To provide a disease/constitution analysis method capable of analyzing the risk of developing a disease using a specimen collected by a simple method.SOLUTION: Exosomes are extracted from specimens collected by non-invasive means, and among the microRNAs present in the exosomes, at least one of miR-141, miR-200a, miR-200c, miR-200b, miR-203, miR-205, miR-214, let-7a, miR-1229, miR-1246, miR-150, miR-223, miR-23a, miR-4644, miR-3976, miR-4306, miR-17-5p, miR-19a, miR-146a, miR-718, miR-375, miR-1290, miR-101, miR-373, miR-320, and miR-574-3p is quantified, and based on the amount of microRNA, the state of a specific disease and/or a particular constitution is analyzed.SELECTED DRAWING: Figure 4 【課題】簡便な方法により採取した検体を用いて疾患の発症リスクの分析を行うことができる疾患・体質の分析方法を提供する。【解決手段】非侵襲の手段により採取した検体からエクソソームを抽出し、前記エクソソーム中に存在するmicroRNAのうち、miR-141、miR-200a、miR-200c、miR-200b、miR-203、miR-205、miR-214、let-7a、miR-1229、miR-1246、miR-150、miR-223、miR-23a、miR-4644、miR-3976、miR-4306、miR-17-5p、miR-19a、miR-146a、miR-718、miR-375、miR-1290、miR-101、miR-373、miR-320、miR-574-3pのうちの少なくとも１つを定量し、microRNA量に基づいて特定の疾患および／または特定の体質の状態を分析する。【選択図】図４